Genco Gencdal
Department of Gastroenterology, Koc University School of Medicine, Istanbul, Turkey
Zeki Karasu
Department of Gastroenterology, Ege University School of Medicine, Izmir, Turkey
Ramazan Idilman
Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey
Murat Kiyici
Department of Gastroenterology, Uludag University School of Medicine, Bursa, Turkey
Sedat Karademir
Department of Gastroenterology, Güven Hospital, Ankara, Turkey
Gokhan Kabacam
Department of Gastroenterology, Güven Hospital, Ankara, Turkey
Murat Harputluoglu 0
Department of Gastroenterology, Liver Transplantation Institute, İnönü University School of Medicine, Malatya, Turkey
Merve Gurakar
Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey
Elif Sertesen
Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey
Hale Gokcan
Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey
Mesut Akarsu
Department of Gastroenterology, Dokuz Eylül University School of Medicine, İzmir, Turkey
Murat Dayangac
Center for Organ Transplantation, Medipol University Hospital, Istanbul, Turkey
Nilay Danis
Department of Gastroenterology, Ege University School of Medicine, Izmir, Turkey
Yasemin Balaban
Department of Gastroenterology, Hacettepe University School of Medicine, Ankara, Turkey
Murat Aladag
Department of Gastroenterology, Turgut Özal University School of Medicine, Malatya, Turkey
Murat Akyildiz
Department of Gastroenterology, Koc University School of Medicine, Istanbul, Turkey
Meral Akdogan
Department of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey
Gupse Adali
Department of Gastroenterology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey
Ilker Turan
Department of Gastroenterology, Ege University School of Medicine, Izmir, Turkey
Soner Onem
Department of Gastroenterology, Ege University School of Medicine, Izmir, Turkey
Abstract
The combination of hepatitis B immunoglobulin and potent nucleos(t)ide analogs after liver transplantation is considered as the standard of care for prophylaxis against hepatitis B virus recurrence. However, the recommended doses, route of administration, and duration of HBIG administration remain unclear. Moreover, hepatitis B immunoglobulin-free prophylaxis with potent nucleos(t)ide analogs has shown promising disease outcomes in preventing hepatitis B virus recurrence. The current recommendations, produced by the Turkish Association for the Study of the Liver, Acute Liver Failure and Liver Transplantation Special Interest Group, suggest a reduced need for hepatitis B immunoglobulin administration with effective long-term suppression of hepatitis B virus replication using potent nucleos(t) ide analogs after liver transplantation.<br>
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Cite this article as: Akarsu M, Onem S, Turan I, et al. Recommendations for hepatitis B immunoglobulin and antiviral prophylaxis against hepatitis B recurrence after liver transplantation. Turk J Gastroenterol. 2021; 32(9): 712-719.
