Gastrointestinal Endoscopy - Original Article
Vol. 29 No. 2 (2018): 2018.29.2-Turkish Journal of Gastroenterology
Safety of simultaneous endoscopic submucosal dissection for two large colorectal neoplasias in the same patient
Main Article Content
Abstract
Background/Aims: Multiple large colorectal lesions requiring endoscopic submucosal dissection (ESD) are sometimes diagnosed during colonoscopy. We evaluated the feasibility and safety of ESD of two colorectal lesions in one session.
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Materials and Methods: The lesions of 16 patients who underwent two ESD procedures in a single session (double ESD group) from November 2009 to July 2014 were matched with those of 64 patients who underwent a single ESD procedure (single ESD group) based on the size and location of the lesion and presence of submucosal fibrosis.
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Results: The net ESD time per patient was longer in double ESD group than in single ESD group (104.0±36.2 vs. 59.1±39.2 min, p<0.001). The net ESD time per lesion tended to be shorter in double ESD group than in single ESD group (49.6±30.0 vs. 59.1±39.2 min, p=0.077). The en bloc resection and curative resection rates did not differ between double ESD and single ESD groups (93.8 % vs. 98.4%, p=0.262; 90.6 % vs. 84.4 %, p=0.534, respectively). The intra- and postprocedural bleeding rates were 12.5% and 0% in double ESD group and 15.6% and 3.1% in single ESD group, respectively. Perforation occurred in two (6.3%) in double ESD group and in six (9.4%) in single ESD group (p=0.715).
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Conclusion: Compared with the single ESD, two simultaneous colorectal ESD procedures in a patient did not increase complications; the en bloc and curative resection rates were similar when performed a single ESD procedure and two simultaneous ESD procedures.
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Cite this article as: Kwak MS, Yang DH, Hwang SW, et al. Safety of simultaneous endoscopic submucosal dissection for two large colorectal neoplasias in the same patient. Turk J Gastroenterol 2018; 29: 183-90.