Assessment of presence and grade of activity in ileal Crohn’s disease

Abstract

Background/Aims: To assess the sensitivity of magnetic resonance enterography (MRE) in the diagnosis of Crohn’s disease (CD) activity and correlation between endoscopic and MRE scores in predicting the activity grade.
 
<strong style="font-size: 12px;">Materials and Methods<span style="font-size: 12px;">: Twenty-five ileal CD patients with clinical and biochemical evidence of activation underwent ileocolonoscopy and MRE within 7 days of their application. Simplified endoscopic scoring of CD (SES-CD) and MRE scores was done and compared with each other and other parameters of activation (CRP, leukocyte count, platelet count).</span>
 
<strong style="font-size: 12px;">Results<span style="font-size: 12px;">: The sensitivity of MRE scoring was found to be 92%; however, the statistical correlation with SES-CD was not significant (p=0.83) for the grading of the activity.</span>
 
<strong style="font-size: 12px;">Conclusion<span style="font-size: 12px;">: MRE scoring is sensitive enough to use in CD activity evaluation; however, it can not be used alone, and it is rather a complementary technique to endoscopy and is especially valuable for patients with extraluminal disease. </span>
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